Enteral compositions for the prevention and/or treatment of...

Details Enteral compositions for the prevention and/or treatment of... Enteral compositions for the prevention and/or treatment of...

A - Human Necessities

61

K

A61K 31/66 (2006.01) A23J 7/00 (2006.01) A23K 1/16 (2006.01) A23K 1/165 (2006.01) A23K 1/18 (2006.01) A23L 1/29 (2006.01) A23L 1/32 (2006.01) A61K 31/07 (2006.01) A61K 31/122 (2006.01) A61K 39/395 (2006.01) A61P 31/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2455012

The present invention relates to an enteral composition containing phospholipids, triglycerides and cholesterol or precursors thereof, which can be used in the treatment of sepsis. With the composition of the invention the natural level of chylomicrons is maintained, in particular in gut associated lymphoid tissue (GALT), which ensures that most of LPS and/or LTA which are released in the body can be neutralized, substantially decreasing the risk of locally occurring high levels of LPS and/or LTA and thus sepsis.

L'invention concerne une composition entérale contenant des phospholipides, des triglycérides et du cholestérol ou des précurseurs de celui-ci, qui peut être utilisée pour traiter une sepsie. La composition de l'invention permet de maintenir les niveaux naturels de chylomicrons, notamment dans le système lymphoïde du tube digestif (GALT), ce qui permet de neutraliser la majorité des lipopolysaccharides et/ou l'acide lipotéichoïque libérés dans le corps, et de réduire le risque local de niveaux élevés de lipopolysaccharides et/ou d'acide lipotéichoïque et donc le risque de sepsie.

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