Enterococcus faecalis polynucleotides and polypeptides

Details Enterococcus faecalis polynucleotides and polypeptides Enterococcus faecalis polynucleotides and polypeptides

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 39/09 (2006.01) C07K 14/315 (2006.01) C07K 16/12 (2006.01) C12N 1/21 (2006.01) C12N 5/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2289116

The present invention relates to novel genes from Enterococcus faecalis and the polypeptides they encode. Also provided are vectors, host cells, antibodies and methods for producing the same. The invention additionally relates to diagnostic methods for detecting Enterococcus nucleic acids, polypeptides and antibodies in a biological sample. The present invention further relates to novel vaccines for the prevention or attenuation of infection by Enterococcus.

Cette invention, qui a trait à des gènes issus d'Enterococcus faecalis et aux polypeptides qu'ils codent, concerne également des vecteurs, des cellules hôtes, des anticorps et leurs procédés de production. Elle concerne encore des méthodes diagnostiques permettant la détection d'acides nucléiques, de polypeptides et d'anticorps d'Enterococcus faecalis dans un prélèvement biologique ainsi que de nouveaux vaccins aux fins de la prévention de l'infection occasionnée par Enterococcus faecalis ou de l'atténuation de celle-ci.

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