Entrapping additives in carbohydrate bodies

A - Human Necessities – 61 – K

Patent

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A61K 9/16 (2006.01)

Patent

CA 2297418

The present invention is a method of entrapping an additive within carbohydrate bodies. The additive is drawn into the internal structure as a fluid during transformation of the bodies from a substantially amorphous state to a crystalline state. The present invention is also a delivery system including a carbohydrate body having an internal free volume space defined by an at least partially crystalline structure at equilibrium conditions, and an additive loaded within the carbohydrate body.

La présente invention concerne un procédé de piégeage d'un additif à l'intérieur de corps glucidiques. Les additifs sont attirés sous forme de fluide dans la structure interne pendant le passage des corps d'un état sensiblement amorphe à un état cristallin. L'invention concerne en outre un système de transport incluant un corps glucidique présentant un espace interne de volume libre délimité par une structure au moins partiellement cristalline à des conditions d'équilibrage, et un additif chargé à l'intérieur du corps glucidique.

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