Environmentally regulated genes of streptococcus suis

Details Environmentally regulated genes of streptococcus suis Environmentally regulated genes of streptococcus suis

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 35/74 (2006.01) A61K 39/09 (2006.01) A61K 48/00 (2006.01) C07K 14/315 (2006.01) C07K 16/12 (2006.01) C12N 1/21 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2436530

The invention relates to the field of diagnosis of and vaccination against Streptococcal infections and to the detection of virulence markers of Streptococci. The invention provides a method for modulating virulence of a Streptococcus comprising modifying a genomic fragment of said Streptococcus wherein said genomic fragment comprises at least a functional part of a fragment identifiable by hybridisation in Streptococcus suis to a nucleic acid or fragment thereof.

L'invention concerne le domaine du diagnostic, de la vaccination contre des infections et de la détection de marqueurs de virulence des streptocoques. L'invention concerne également une méthode permettant de moduler la virulence d'un streptocoque qui consiste à modifier un fragment génomique dudit streptocoque, ledit fragment génomique comprenant au moins une partie fonctionnelle de fragment identifiable par hybridation dans Streptococcus suis avec un acide nucléique ou un fragment de celui-ci.

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