Enzymatic assay of hiv protease inhibitors

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/37 (2006.01) A61K 38/55 (2006.01) A61P 31/18 (2006.01) G01N 33/569 (2006.01) G01N 33/573 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2432925

A method of quantifying an HIV protease inhibitor in a biological sample includes combining HIV protease, a spectroscopic substrate for HIV protease, and a biological sample suspected of containing an HIV protease inhibitor to form an assay mixture. A spectroscopic property of the assay mixture may be measured and related to the concentration of the HIV protease inhibitor in the biological sample.

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