Enzymatic high range glucose test

Details Enzymatic high range glucose test Enzymatic high range glucose test

C - Chemistry, Metallurgy

12

Q

150/15.1, 150/3.

C12Q 1/54 (2006.01) G01N 33/52 (2006.01)

Patent

CA 1246974

ABSTRACT OF THE DISCLOSURE A test composition comprising glucose oxidase, a peroxidatively active component, a chromogenic indicator system capable of providing a detectable response and a borate buffer capable of providing an initial pH above about pH 7 is particularly useful for the semiquantitative determination of high range glucose, (i.e. glucose concentrations of 1,000 mg/dL to 10,000 mg/dL). A preferred indicator system is a water soluble iodide salt and poly- (vinylpyrrolidone). The use of a borate buffer capable of providing an initial pH above about pH 7 permits greatly improved resolution for the semi- quantitative determination of high range glucose when the test composition is incorporated onto a carrier matrix to prepare a solid state unitary test device.

486939

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