C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 4/12 (2006.01) A61K 38/04 (2006.01) C12P 21/06 (2006.01) A61K 7/40 (2000.01) A61K 7/48 (2000.01)
Patent
CA 2296311
The present invention relates to a mixture of soluble hydrophobic peptides of an enzymatic hydrolysate of milk having skin hydrating properties and percutaneous absorption levels of 4 to 5%. The mixture also exhibits wound healing properties but does not have the allergenicity of the milk-protein. One fraction of the mixture is capable of increasing in vitro the growth rate of cell-cultured keratinocytes by at least 50%. Another fraction is capable of increasing the growth rate of cell-cultured fibroblasts by 37% and the production of collagen by 73%. The hydrolysate and peptides of the present invention can be formulated in cosmetic composition, in skin cell culture medium and in wound healing composition.
Amiot Jean
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Universite Laval
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