Enzymatic hydroxylation process for the preparation of...

Details Enzymatic hydroxylation process for the preparation of... Enzymatic hydroxylation process for the preparation of...

C - Chemistry, Metallurgy

12

P

C12P 17/06 (2006.01) A61K 31/215 (2006.01) A61K 31/35 (2006.01) A61K 31/365 (2006.01) C12P 7/02 (2006.01) C12P 7/62 (2006.01) C12P 13/00 (2006.01)

Patent

CA 2134025

Abstract ENZYMATIC HYDROXYLATION PROCESS FOR THE PREPARATION OF HMG-CoA REDUCTASE INHIBITORS AND INTERMEDIATES THEREOF An enzymatic hydroxylation process for the preparation of compounds useful as HMG-CoA reductase inhibitors and/or as intermediates in the preparation of HMG-CoA reductase inhibitors uses a microorganism or an enzyme derived from, or having the structure of an enzyme derived from, said microorganism, which is capable of catalyzing the hydroxylation process.

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