Enzymatic l-aspartyl-l-phenylalanine alkyl ester production

C - Chemistry – Metallurgy – 12 – P

Patent

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195/123, 195/128

C12P 21/02 (2006.01) C07K 5/072 (2006.01) C12N 9/00 (2006.01)

Patent

CA 1339674

The invention relates to a method of producing L-aspartyl-L-phenylalanine alkyl ester comprising reacting L-aspartic acid alpha ester or amide with L-phenylalanine alkyl ester in the presence of an enzyme which cleaves aspartic acid from the alpha ester or amide to yield L-aspartyl-L-phenylalanine alkyl ester by condensation. The product is useful as a sweetener.

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