Enzymatic oxidations

Details Enzymatic oxidations Enzymatic oxidations

C - Chemistry, Metallurgy

12

P

C12P 17/00 (2006.01) C07D 231/52 (2006.01) C07D 239/52 (2006.01) C07D 239/69 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/04 (2006.01) C07D 405/14 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C12P 11/00 (2006.01) C12P 13/00 (2006.01)

Patent

CA 2349057

The following invention relates to a process for oxidising alkyl groups attached directly or via a linker, to a sulfonamide moiety (II) by the use of cytochrome P450 enzymes, to give the corresponding alcohol or carboxylic acid (I). R-NHSO2-X-Y-CH3 (II) (see formula) R-NHSO2-X-Y-Z (I) wherein R is an organic radical, X is a linker, Y is -C(CH3)2- or -CH(CH3)- and Z is - CH2OH or -COOH.

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