Enzymatic preparation of chiral epoxide or hydroxy compounds...

C - Chemistry – Metallurgy – 12 – P

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C12P 17/18 (2006.01) C07D 311/22 (2006.01) C07D 311/70 (2006.01) C07D 493/04 (2006.01) C12P 17/06 (2006.01) C12P 41/00 (2006.01)

Patent

CA 2124733

Abstract ENZYMATIC PREPARATION OF CHIRAL EPOXIDE OR HYDROXY COMPOUNDS BY STEREOSELECTIVE EPOXIDATION OR HYDROXYLATION An enzymatic process for the preparation of chiral epoxides, monohydroxy or dihydroxy compounds of formula I Image ; and II Image by the stereoselective epoxidation or hydroxylation of benzopyrans of formula III Image or resolution of compounds of formula IIa Image . The compounds of formula I and II are intermediates useful in the preparation of pyranyl cyanoguanidine derivatives.

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