Enzymatic process for producing gdp-alpha-d-mannose, a gdp...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/12 (2006.01) C12N 1/21 (2006.01) C12N 9/90 (2006.01) C12P 19/24 (2006.01) C12P 19/30 (2006.01) C12P 19/32 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2214458

The invention concerns a GDP-mannose-pyrophosphorylase. The aim of the invention is to produce a GDP-mannose-pyrophosphorylase which can be obtained for an acceptable outlay and does not cause problems, in particular because of its monofunctionality, in continuous multiple stage processes. To that end, a mannose- or mannose-derivative-specific GDP-mannose-pyrophosphorylase, which can be isolated from microorganisms and has a specific activity of 2 U/mg, is prepared.

La présente invention concerne une GDP mannose pyrophosphorylase. L'objectif de l'invention était d'obtenir une GDP mannose pyrophosphorylase à un coût acceptable et qui, en particulier en raison de sa monofonctionnalité, ne provoque pas de problèmes à long terme dans des processus continus à plusieurs phases. Dans ce but, l'invention propose une GDP mannose pyrophosphorylase spécifique de la mannose ou de dérivés de la mannose, pouvant être isolée dans des microorganismes, et dont l'activité spécifique est supérieure ou égale à 2 U/mg.

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