Enzymatic production of 7-amino cephalosporanic acid

Details Enzymatic production of 7-amino cephalosporanic acid Enzymatic production of 7-amino cephalosporanic acid

C - Chemistry, Metallurgy

12

P

C12P 35/00 (2006.01) C12N 1/14 (2006.01) C12N 1/16 (2006.01) C12N 1/20 (2006.01) C12P 35/02 (2006.01)

Patent

CA 2049958

2049958 9012110 PCTABS00002 An enzymatic process for the production of 7-amino cephalosporanic acid from cephalosporine C is disclosed. The process is a two-stage enzymatic reaction which can be performed in a single reactor. The invention further includes a mutant strain of Trigonopsis variabilis which produces increased amounts of D-amino acid oxidase, and a mutant strain of Acinetobacter spp., which increased amounts of deacylase, which are enzymes necessary for the present process.

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