C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 17/12 (2006.01)
Patent
CA 2268539
A process for an enzymatic production of vitamin B6 which comprises incubating 1-deoxy-D-threo-pentulose and 4-hydroxy-L-threonine with an enzyme reaction system prepared from cells of microorganism belonging to genus Rhizobium, Sinorhizobium, Flavobacterium, Chryseobacterium, Lactobacillus, Arthrobacter, Bacillus, Klebsiella, Escherichia, Pseudomonas, Stenotrophomonas, Enterobacter, Serratia, Corynebacterium, Brevibacterium, Exiguobacterium, Saccharomyces, Yamadazma, Pichia and Candida, in the presence of NADP+, NAD+, ATP. Manganese and magnesium ions stimulate the above reaction. This process affords high yields of vitamin B6, a vitamin essential for the nutrition of animals, plants and microorganisms, and useful as a medicine or food additive.
Hoshino Tatsuo
Tazoe Masaaki
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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