C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 41/00 (2006.01) C12P 13/00 (2006.01)
Patent
CA 2136840
The present invention relates to the enzymatic resolution of a racemic mixture of stereospecific, pharmaceutically useful in vivo inhibitors of .gamma.-aminobutyric acid transaminase (GABA-T), specifically .gamma.-ethynyl GABA, .gamma.-vinyl GABA and .gamma.-allenyl GA- BA using penicillin acylase (PA).
Merrell Dow Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
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