Enzymatic synthesis of enatiopure intermediates by means of...

C - Chemistry – Metallurgy – 12 – P

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C12P 41/00 (2006.01) C07D 207/26 (2006.01)

Patent

CA 2539037

The present invention relates to a process for the preparation of enantiopure intermediates useful in the synthesis of valuable pharmaceutically active compounds, e.g. MAOB inhibitors, and to novel intermediates of formulae (I) and (II) wherein R21, R22, R23 and R24 are as defined in the description and claims.

Procédé de préparation d'intermédiaires énantiopurs utiles dans la synthèse de composés de valeur actifs sur le plan pharmaceutique, par ex. des inhibiteurs de MAOB, et nouveaux intermédiaires de formule (I) et (II) dans lesquelles R?21¿, R?22¿, R?23¿ et R?24¿ sont tels que définis dans le descriptif et dans les revendications.

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