Enzymatic synthesis of gangliosides

C - Chemistry – Metallurgy – 12 – P

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C12P 19/18 (2006.01) C12P 19/04 (2006.01) C12P 19/12 (2006.01) C12P 19/26 (2006.01) C12P 19/44 (2006.01) C12P 7/64 (2006.01)

Patent

CA 2312843

This invention provides methods for practical in vitro synthesis of gangliosides and other glycolipids. The synthetic methods typically involve enzymatic synthesis, or a combination of enzymatic and chemical synthesis. One or more of the enzymatic steps is preferably carried out in the presence of an organic solvent.

Cette invention concerne des méthodes de synthèse in vitro pratiques de gangliosides et autres glycolipides. Les méthodes de synthèse font habituellement intervenir la synthèse enzymatique, ou une combinaison de synthèse enzymatique et de synthèse chimique. Une ou plusieurs étapes enzymatiques sont de préférence exécutées en la présence d'un solvant organique.

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