Enzymatic synthesis of l-serine

C - Chemistry – Metallurgy – 12 – N

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195/134.2, 195/1

C12N 1/20 (2006.01) C12N 9/10 (2006.01) C12N 11/02 (2006.01) C12P 13/06 (2006.01)

Patent

CA 1217158

ABSTRACT L-serine is synthesized from glycine and form- aldehyde in the presence of biocatalytic amounts of serine hydroxymethyltransferase and tetrahydrofolate under L-serine producing conditions, wherein the am- ount of tetrahydrofolate is sufficient to protect the serine hydroxymethyltransferase from being in- activated by the formaldehyde.

441483

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