Enzyme-based gprotein-coupled receptor assay

G - Physics – 01 – N

Patent

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G01N 33/566 (2006.01) C07H 21/04 (2006.01) C07K 14/00 (2006.01) C12N 15/12 (2006.01)

Patent

CA 2399874

Methods for detecting G-protein coupled receptor (GPCR) activity; methods of assaying GPCR activity; and methods of screening for GPCR ligands, G-protein- coupled receptor kinase (GRK) activity, and compounds that interact with components of the GPRC regulatory process are described.

L'invention concerne des procédés de détection de l'activité de récepteurs couplés aux protéines G (GPCR) ; des méthodes de dosage de l'activité de GPCR ; et des méthodes de criblage de ligands de GPCR, de l'activité de kinases de la famille des GRK, et de composés qui interagissent avec des composants du processus régulatoire de GPRC.

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