Enzyme-inhibiting urea derivatives of dipeptides, a process...

C - Chemistry – Metallurgy – 07 – K

Patent

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530/5.06, 167/10

C07K 5/06 (2006.01) A61K 38/05 (2006.01) C07K 5/065 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2005023

- 1 - Abstract of the disclosure Enzyme-inhibiting urea derivatives of dipeptides, a process for the preparation thereof, agents containing these, and the use thereof The present invention relates to compounds of the formula I Image (I) in which A and B denote, independently of one another, an amino acid, X as desired can be absent or represents -O-, -S-, - CF2-, -CO- or -CHR8, p and q denote, independently of one another, 0, 1, 2, 3 or 4, and R1 to R4 are defined in the description, as well as the salts thereof. The invention furthermore relates to a process for the preparation of the compounds of the formula I and to the use thereof as medicines.

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