C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
530/15.04, 195/1
C12P 7/40 (2006.01) A61K 35/74 (2006.01) C07H 19/16 (2006.01) C12N 9/99 (2006.01) C12P 1/06 (2006.01)
Patent
CA 1174622
ABSTRACT OF THE DISCLOSURE A new compound, named "Griseolic Acid", and its pharmaceutically acceptable salts have enzyme inhibitory activity and can be prepared by the cultivation of certain microorganisms of the genus streptomyces, especially Strepto- myces griseoaurantiacus SANK 63479 (FERM-P 5223). Griseolic acid and its pharmaceutically acceptable salts inhibit the activity of the enzyme cyclic adenosine monophosphate phos- phodiesterase and, as a result of this, have a variety of phusiological activities and uses.
364386
Iwado Seigo
Naito Atsushi
Nakagawa Fumio
Okazaki Takao
Terahara Akira
Marks & Clerk
Sankyo Company Limited
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