Enzyme treated bcg vaccine and process therefor

A - Human Necessities – 61 – K

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A61K 39/04 (2006.01)

Patent

CA 2073778

Mycobacterium bovis BCG suspensions are treated with a protease enzyme such as pronase, resulting in the production of suspensions having smaller aggregates and single cells. Such suspensions, when processed into vaccines, exhibit improved immunizing potential against cancer and would be expected to exhibit improved immunizing potential against tuberculosis.

On traite des suspensions de Mycobacterium bovis BCG à l'aide d'une enzyme de protéase telle que la pronase, ayant pour résultat la production de suspensions présentant des agrégats plus petits et des cellules individuelles. Ladite suspension, une fois traitée pour obtenir des vaccins, présente un potentiel immunisant amélioré contre le cancer, et on pense qu'elle présente un potentiel immunisant amélioré contre la tuberculose.

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