Enzymes and methods for producing omega-3 fatty acids

Details Enzymes and methods for producing omega-3 fatty acids Enzymes and methods for producing omega-3 fatty acids

C - Chemistry, Metallurgy

12

N

C12N 15/82 (2006.01) A01H 5/00 (2006.01) A01H 5/10 (2006.01) C12N 15/84 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2743880

The present invention relates generally to the field of recombinant fatty acid synthesis, particularly in transgenic plants. The application describes genes involved in fatty acid synthesis and provides methods and vectors for the manipulation of fatty acid composition of plant oils. In particular, the invention provides constructs for achieving the integration of multiple heterologous genes involved in fatty acid synthesis into the plant genome, such that the resulting plants produce altered levels of polyunsaturated fatty acids. Also described are methods for enhancing the expression of fatty acid biosynthesis enzymes by co-expressing a silencing suppressor within the plant storage organ.

La présente invention se rapporte généralement au domaine de la synthèse recombinante d'acides gras, notamment chez les plantes transgéniques. On décrit des gènes impliqués dans la synthèse d'acides gras, et des méthodes et des vecteurs servant à manipuler la composition en acides gras d'huiles végétales. L'invention concerne en particulier des constructions destinées à l'intégration dans le génome végétal de plusieurs gènes hétérologues impliqués dans la synthèse d'acides gras, de sorte que les plantes résultantes produisent des taux modifiés d'acides gras polyinsaturés. L'invention concerne en outre des méthodes qui amélorent l'expression d'enzymes de biosynthèse d'acides gras par coexpression d'un suppresseur de silencing dans l'organe de stockage des plantes.

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