Enzymes combinations for destroying proliferative cells

Details Enzymes combinations for destroying proliferative cells Enzymes combinations for destroying proliferative cells

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 31/70 (2006.01) A61K 38/45 (2006.01) A61K 48/00 (2006.01) C12N 9/12 (2006.01) C12N 9/96 (2006.01) C12N 15/62 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2248629

Enzyme combinations useful for destroying cells, particularly proliferative cells, are disclosed. Vectors enabling the intracellular expression and transfer of said enzyme combinations, as well as the therapeutical use thereof, particularly in anti-cancer gene therapy, are also disclosed.

La présente invention concerne des combinaisons d'enzymes, utilisables pour la destruction de cellules, notamment de cellules prolifératives. Elle concerne également des vecteurs permettant le transfert et l'expression intracellulaire de ces combinaisons d'enzymes, ainsi que leur utilisation thérapeutique, en particulier en thérapie génique anti-cancéreuse.

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