Enzymes for pharmaceutical use

A - Human Necessities – 61 – K

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A61K 38/48 (2006.01) A61P 1/14 (2006.01) A61P 1/18 (2006.01) A61P 3/10 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2586222

The pharmaceutical use of proteases related to a protease derived from Nocardiopsis sp. NRRL 18262 (SEQ ID NO: 1), optionally in combination with a lipase and/or an amylase. Examples of medical indications are: Treatment of digestive disorders, pancreatic exocrine insufficiency (PEI), pancreatitis, cystic fibrosis, diabetes type I, and/or diabetes type II.

L'invention concerne l'utilisation pharmaceutique de protéases liées à une protéase dérivée de Nocardiopsis sp. (NRRL 18262) (SEQ ID NO: 1), éventuellement en combinaison avec une lipase et/ou une amylase. On trouve comme exemples d'utilisations médicales : traitement de troubles digestifs, d'insuffisance pancréatique exocrine, de pancréatite, de fibrose kystique, de diabète de type I et/ou de diabète de type II.

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