Enzymes having dehalogenase activity and methods of use thereof

Details Enzymes having dehalogenase activity and methods of use thereof Enzymes having dehalogenase activity and methods of use thereof

C - Chemistry, Metallurgy

12

N

C12N 15/55 (2006.01) C07H 21/04 (2006.01) C07K 16/40 (2006.01) C12N 9/14 (2006.01) C12N 15/63 (2006.01) C12P 7/20 (2006.01) C12P 7/40 (2006.01) C12P 19/34 (2006.01) C12Q 1/34 (2006.01) G06F 17/00 (2006.01)

Patent

CA 2430192

The invention relates to haloalkane dehalogenases and to polynucleotides encoding the haloalkane dehalogenases. In addition methods of designing new dehalogenases and method of use thereof are also provided. The dehalogenases have increased activity and stability at increased pH and temperature.

Cette invention concerne des haloalcane déshalogénases et des polynucléotides codant les haloalcane déshalogénases. En outre, ladite invention concerne aussi des méthodes de désignation de nouvelles déshalogénases et une méthode d'utilisation correspondante. Les déshalogénases présentent une stabilité et une activité accrues à un pH et à une température élevés.

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