Eosinophil-specific apoptosis inducer

Details Eosinophil-specific apoptosis inducer Eosinophil-specific apoptosis inducer

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61P 11/06 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) A61P 43/00 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2402477

An apoptosis inducer and a remedy for eosinophilic diseases containing as the active ingredient an antibody which reacts specifically with eosinophils and induces the apoptosis of eosinophils; and a method of inducing eosinophil- specific apoptosis and a method of specifically reducing or eliminating eosinophils in peripheral blood or a tissue infiltrated with eosinophils with the use of the above antibody.

L'invention concerne un inducteur de l'apoptose et un remède destiné aux maladies éosinophiliques contenant comme principe actif un anticorps qui réagit de manière spécifique aux éosinophiles et qui induit l'apoptose des éosinophiles. L'invention concerne également un procédé d'induction de l'apoptose spécifique à l'éosinophilie ainsi qu'un procédé de réduction ou d'élimination spécifique des éosinophiles dans le sang périphérique ou un tissu infiltré d'éosinophiles au moyen de l'anticorps susmentionné.

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