Eph receptor tumor biomarkers

Details Eph receptor tumor biomarkers Eph receptor tumor biomarkers

G - Physics

01

N

G01N 33/574 (2006.01) C07K 14/82 (2006.01) C07K 16/30 (2006.01)

Patent

CA 2584804

Specific, differential expression of EphA2 in both GBM cells and human GBM tumors compared to normal brain are shown. EphA2 serves as a useful molecular marker for cancer in such areas as diagnosis and prognosis. In addition, EphA2 is used in the development of new therapeutics for tumors, such as molecularly targeted drug delivery.

L'invention concerne l'expression différentielle, spécifique, du récepteur EphA2 dans des cellules GBM et des cellules GBM humaines par rapport à des cellules saines du cerveau. Le récepteur EphA2 sert de marqueur moléculaire pour le diagnostic et le pronostic du cancer. Le récepteur EphA2 est également utilisé pour la mise au point de nouveaux moyens de traitement du cancer, tels que l'administration de médicaments ciblée au niveau moléculaire.

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