Epidermal stimulation to enhance hair follicle formation

A - Human Necessities – 61 – K

Patent

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A61K 35/36 (2006.01) A61K 8/98 (2006.01) A61Q 7/00 (2006.01)

Patent

CA 2700311

The present invention features a method for improving the efficiency of hair formation by follicular cell implantation. The method includes the use of epidermal stimulation (ES) to stimulate keratinocytes in a subject's skin in order to make them more receptive to hair inductive signals originating from implanted follicular cells (e.g. dermal papilla cells, dermal sheath cells, and/or outer root sheath cells).

La présente invention porte sur un procédé pour améliorer l'efficacité de la formation de cheveux par implantation de cellules folliculaires. Le procédé comprend l'utilisation d'une stimulation épidermique (ES) pour stimuler les kératinocytes dans la peau d'un sujet afin de les rendre plus réceptifs à des signaux favorisant la pousse de cheveux provenant de cellules folliculaires implantées (par exemple, cellules de papille dermique, cellules de gaine dermique et/ou cellules de gaine de racine externe).

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