Epigenetic silencing of cyclooxygenase-2 affects clinical...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2690879

The present invention discloses methods of using the methylation status of the COX-2 gene promoter region as a biomarker for a gastric cancer patient to determine a prognosis and a treatment regimen, and to monitor the progress of a treatment regimen.

La présente invention concerne des procédés permettant d'utiliser le statut de méthylation de la région promoteur du gène COX-2 en tant que biomarqueur chez un patient souffrant d'un cancer gastrique afin d'établir un pronostic et un régime thérapeutique, ainsi que de surveiller le progrès d'un régime thérapeutique.

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