Episomal vector and uses thereof

Details Episomal vector and uses thereof Episomal vector and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) A01K 67/027 (2006.01) A61K 48/00 (2006.01) C12N 15/37 (2006.01) C12N 15/68 (2006.01) C12P 19/34 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2241172

The invention relates to a recombinant vector for stable persistence of exogenous DNA in a eukaryotic host cell, and the uses of the recombinant vector for long-term stable production of a gene product in the host cell, the vector including the minimal origin of replication of papillomavirus and the minichromosomal maintenance element of papillomavirus.

L'invention a trait à un vecteur de recombinaison aux fins d'une rémanence stable d'un ADN érogène dans une cellule hôte eucaryote ainsi qu'à l'utilisation qui en est faite pour produire à long terme et de façon stable un produit génique dans la cellule hôte, ce vecteur comprenant le principe minimal de réplication d'un papillomavirus et l'élément minichromosomique de rémanence du virus.

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