Epo d + 5-fu/gemcitabine

Details Epo d + 5-fu/gemcitabine Epo d + 5-fu/gemcitabine

A - Human Necessities

61

K

A61K 31/7068 (2006.01) A61K 31/427 (2006.01) A61K 31/429 (2006.01) A61K 31/513 (2006.01) A61K 31/7088 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2499682

Methods and compositions for treating hyperproliferative diseases using combinations of one or more epothilones and one or more nucleoside analogs. In some embodiments, the combination includes epothilone D and 5-fluorouracil or 5'-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]-cytidine.

L'invention concerne des procédés et des compositions pour le traitement de maladies hyperprolifératives au moyen de combinaisons d'une ou plusieurs épothilones et d'un ou plusieurs analogues de nucléoside. Sous certaines variantes, on décrit une combinaison d'épothilone D et de 5-fluoro-uracile ou de 5'-désoxy-5-fluoro-N-[(pentyloxy)carbonyle]-cytidine.

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