Epothilone c, d, e and f, production process, and their use...

Details Epothilone c, d, e and f, production process, and their use... Epothilone c, d, e and f, production process, and their use...

C - Chemistry, Metallurgy

07

D

C07D 417/06 (2006.01) A01N 43/78 (2006.01) A01N 43/90 (2006.01) A01N 63/02 (2006.01) A61K 31/425 (2006.01) C07D 493/04 (2006.01) C12P 17/08 (2006.01) C12P 17/16 (2006.01) C12P 17/18 (2006.01)

Patent

CA 2269118

The present invention concerns the epothilone, especially epothilone C (R = hydrogen) and epothilone D (R = methyl) of formula (I), as well as epothilone E (R = hydrogen) and epothilone F (R = methyl) of formula (II), the production process and their application for producing therapeutic agents, including cytostatic agents, as well as phytosanitary agents.

La présente invention concerne l'épothilone, notamment l'épothilone C (R = hydrogène) et l'épothilone D (R = méthyle) correspondant à la formule (I), ainsi que l'épothilone E (R = hydrogène) et l'épothilone F (R = méthyle) correspondant à la formule (II), le mode de préparation de ces produits et leur utilisation dans la préparation d'agents thérapeutiques, y compris cytostatiques, et d'agents phytosanitaires.

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