A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/427 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2501610
The present invention relates to a method of treating a warm-blooded animal, especially a human, having myeloma, especially myeloma which is resistant to conventional cytotoxic chemotherapy, comprising administering to said animal a therapeutically effective amount of an epothilone, especially an epothilone of formula (I), to a combination comprising an epothilone, for simultaneous, separate or sequential use; and to a pharmaceutical composition and a commercial package comprising said combination.
La présente invention concerne un procédé convenant au traitement d'un animal à sang chaud, plus particulièrement d'un humain, porteur de myélome, et plus particulièrement de myélome résistant à la chimiothérapie cytotoxique conventionnelle. En l'occurrence, on administre à l'animal concerné une quantité thérapeutiquement suffisante d'un épothilone, plus particulièrement d'un épothilone représenté par la formule générale (I). L'invention concerne également une association comprenant un épothilone, à usage simultané, séparé, ou séquentiel. L'invention concerne enfin composition pharmaceutique et un nécessaire commercial comprenant cette association.
Anderson Kenneth C.
Griffin James Douglas
Lin Boris
Dana-Farber Cancer Institute Inc
Fetherstonhaugh & Co.
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