Epoxide hydrolases of aspergillus origin

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/55 (2006.01) C12N 1/15 (2006.01) C12N 9/14 (2006.01) C12N 15/80 (2006.01) C12P 7/00 (2006.01) C12P 7/18 (2006.01) C12P 7/22 (2006.01) C12P 13/00 (2006.01) C12P 17/02 (2006.01) C12P 41/00 (2006.01)

Patent

CA 2372097

The invention concerns proteins of fungal origin having an epoxide hydrolase activity, such as those obtained in essentially pure form by extraction from fungi cells, or by culturing in host cells transformed by a nucleotide sequence coding for said fungal proteins. The invention also concerns the uses thereof, in particular for implementing methods for preparing enantiopure epoxides and/or diols.

La présente invention a pour objet des protéines d'origine fongique ayant une activité époxyde hydrolase, telle qu'obtenues sous forme essentiellement pure par extraction à partir de cellules de champignons, ou par mise en culture de cellules hôtes transformées par une séquence nucléotidique codant pour les protéines fongiques susmentionnées, ainsi que leurs utilisations notamment dans le cadre de la mise en oeuvre de procédés de préparation d'époxydes et/ou de diols énantiomériquement purs.

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