Eprosartan dihydrate and a process for its production and...

Details Eprosartan dihydrate and a process for its production and... Eprosartan dihydrate and a process for its production and...

C - Chemistry, Metallurgy

07

D

C07D 409/06 (2006.01) A61K 31/415 (2006.01) A61K 31/4178 (2006.01) A61K 31/44 (2006.01) A61K 31/54 (2006.01) A61K 31/635 (2006.01) A61K 38/55 (2006.01)

Patent

CA 2250395

This invention relates to (E)-.alpha.[2-n-butyl-1-[(4-carboxyphenyl)methyl]-1H- imidazol-5-yl]methylene-2-thiopheneproprionic acid monomethanesulfonate dihydrate, a process for its production, compositions containing the compound and methods of using the compound to block angiotensin II receptors and to treat hypertension, congestive heart failure and renal failure.

Cette invention se rapporte au dihydrate de monométhanesulfonate d'acide (E)- alpha -[2-n-butyl-1-[(4-carboxyphényl)méthyl]-1H-imidazol-5-yl]méthylène-2-thiophènepropionique, à un procédé de fabrication de ce composé, à des compositions contenant ce composé et à des procédés d'utilisation de ce composé qui visent à bloquer les récepteurs de l'angiotensine II et à traiter l'hypertension, l'insuffisance cardiaque globale et l'insuffisance rénale.

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