Epstein-barr virus peptides and antibodies against these...

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 21/08 (2006.01) A61K 39/245 (2006.01) A61K 39/42 (2006.01) C07K 7/08 (2006.01) C07K 14/05 (2006.01) C07K 16/08 (2006.01) C07K 17/00 (2006.01) C12N 5/18 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2120342

The invention relates to a peptide or fragment thereof which is immunochemically reactive with Epstein-Barr Virus (EBV) antibodies. A new monoclonal antibody directed to said peptide or fragment thereof is also part of the invention. The invention also relates to a method for the detection of EBV or anti-EBV antibodies in a test fluid and also to an immunochemical reagent comprising a peptide, a fragment or a polypeptide according to the invention and a test kit to be used_when applying the said detection methods. Detection of EBV in a test fluid or tissue specimen using antibodies, monoclonal and polyclonal, directed to the said peptide, which have the characteristics of detecting both native and denatured intact, functional EBNA-1 protein is also part of said invention.

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