Equilibrative nucleoside transporter ent1 inhibitors

Details Equilibrative nucleoside transporter ent1 inhibitors Equilibrative nucleoside transporter ent1 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 491/10 (2006.01) A61K 31/537 (2006.01) A61P 29/00 (2006.01) C07D 498/10 (2006.01)

Patent

CA 2704423

The present invention is related to novel compounds of formula (I) having equilibrative nucleoside transporter ENT1 inhibiting properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment of diseases linked to the inhibition of ENT1 receptors in animals, in particular humans.

L'invention porte sur de nouveaux composés de formule (I) présentant des propriétés inhibant le transporteur équilibrant des nucléosides ENT1, sur des préparations pharmaceutiques les comprenant, et sur leurs procédés de préparation, et d'utilisation pour le traitement de maladies de l'animal et en particulier de l'homme, liées à l'inhibition des récepteurs du ENT1.

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