Equine-gamma-interferon

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

530/13, 167/103.

C12N 15/23 (2006.01) A61K 38/21 (2006.01) C07K 14/57 (2006.01) C07K 16/24 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1339776

This invention relates to processes for preparing horse gamma interferon (equine interferon-gamma, EqIFN-~), DNA sequences which encode this polypeptide, suitable vectors and host organisms containing these DNA sequences and EqIFN-~ itself. The invention further relates to partial DNA sequences which encode polypeptides which differ structurally from natural EqIFN-~ polypeptide. The use of the proteins is also described. The invention also relates to monoclonal antibodies against such polypeptides, to hybrid cell lines which secrete these antibodies and to processes for preparing them.

553890

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