C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/00 (2006.01) C07K 14/475 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2420062
The present invention concerns methods and means for controlling excessive proliferation and/or migration of smooth muscle cells, and in particular for treating stenosis, by using antagonists of a native ErbB4 receptor. The invention further concerns a method for the identification of ErbB4 agonists and antagonists capable of inhibiting or enhancing the proliferation or migration of smooth muscle cells.
L'invention concerne des procédés et des moyens permettant de réguler une prolifération et/ou une migration excessive de cellules musculaires lisses, et notamment de traiter la sténose, par l'utilisation d'agonistes d'un récepteur ErbB4 natif. L'invention concerne également un procédé d'identification d'agonistes et d'antagonistes de ErbB4 capables d'inhiber ou de favoriser la prolifération ou la migration de cellules musculaires souples.
Gerritsen Mary E.
Sliwkowski Mark X.
Dennison Associates
Genentech Inc.
LandOfFree
Erbb4 antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Erbb4 antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Erbb4 antagonists will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1860276