C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61P 35/00 (2006.01) A61K 31/513 (2006.01) A61K 31/519 (2006.01) A61K 31/555 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2724346
The invention provides compositions and methods for determining the likelihood of successful treatment with a first line FOLFOX chemotherapy regimen or in further combination with PTK/ZK. The methods comprise determining the gene expression levels of a gene of interest and correlating the high or low expression to the predictive response. Patients identified as responsive are then treated with the appropriate therapy.
Linvention concerne des compositions et des procédés pour la détermination de la probabilité de la réussite dun traitement avec un régime de chimiothérapie FOLFOX de première intention ou en combinaison supplémentaire avec PTK/ZK. Les procédés consistent à déterminer les niveaux dexpression génique dun gène dintérêt, et à corréler lexpression élevée ou faible à la réponse prédictive. Les patients identifiés comme étant sensibles au traitement sont ensuite traités à laide de la thérapie appropriée.
Smart & Biggar
University Of Southern California
LandOfFree
Ercc-1 expression predicts chemotherapy outcome does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Ercc-1 expression predicts chemotherapy outcome, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ercc-1 expression predicts chemotherapy outcome will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1890125