Ergothioneine and/or its derivatives as a cell preservative

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 1/04 (2006.01) C12N 5/076 (2010.01) A01N 1/00 (2006.01) A01N 1/02 (2006.01) A01N 3/00 (2006.01)

Patent

CA 2683858

The present invention relates to cell, tissue or derivatives thereof, preserving compositions for cells in culture, storage, or lyophilization. According to the invention ergothioneine is added as a supplement to such extender or preservative compositions. Sperm cells so treated showed increased motility when thawed compared to cells that were not treated with ergothioneine.

L'invention concerne des compositions permettant de conserver les cellules, les tissus ou leurs dérivés, et destinées aux cellules en culture, stockées ou lyophilisées. Selon l'invention, de l'ergothionéine est rajoutée à ces additifs ou à ces compositions de conservation. Le sperme qui a reçu ce traitement a fait preuve d'une plus grande motilité après décongélation que le sperme qui n'a pas été additionné d'ergothionéine.

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