Erodible matrix for sustained release bioactive composition

Details Erodible matrix for sustained release bioactive composition Erodible matrix for sustained release bioactive composition

A - Human Necessities

61

K

167/167, 71/47

A61K 9/26 (2006.01) A01N 25/08 (2006.01) A61K 9/20 (2006.01)

Patent

CA 1246448

ABSTRACT OF THE DISCLOSURE A sustained release composition for releasing a biologically active compound into an aqueous liquid environment comprises said biologically active compound dispersed in a bioerodible matrix, the matrix compris- ing a mixture of 5 to 95 % by weight of a polyethylene glycol having a molecular weight of from about 1000 to about 20,000, and 95 to 5 % by weight of an erosion rate modifier which is an amphiphilic compound insoluble in the aque- ous liquid. Dosage forms comprising the erodible matrix are prepared by molding, particularly by injection molding.

486711

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