Erythromycin a compounds, a process for the manufacture...

C - Chemistry – Metallurgy – 07 – H

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C07H 17/08 (2006.01) C07H 17/00 (2006.01)

Patent

CA 1191843

ABSTRACT OF THE DISCLOSURE NEW ERYTHROMYCIN A COMPOUNDS, A PROCESS FOR THEIR MANUFACTURE AND THEIR USE IN THE CONTROL OF BACTERIA ABSTRACT N-Methyl erythromycin A derivatives which may have alkanoyl substituents in the 13, 14 2' and/or 3" positions, are made by reacting the methyl derivatives with ethylene carbonate and, if required, acylating the product with an appropriate carboxylic acid anhydride. The compounds have activity against a wide range of bacteria.

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