C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 19/62 (2006.01) C07H 17/08 (2006.01) C12N 1/21 (2006.01) C12N 15/52 (2006.01) C12N 15/76 (2006.01)
Patent
CA 2080583
2080583 9116334 PCTABS00007 Novel 6-deoxyerythromycin derivatives are disclosed, as are methods for their preparation and use as antiinfective agents. The compounds of the invention include 6-deoxyerythromycins and 6-deoxy-15-norerythromycins which are represented by the structural formula (I) in which R1 is selected from OH and H, and R2 and R3 are independently selected from H and CH3, as well as the pharmaceutically acceptable salts and esters of the above compounds. Additionally disclosed are genetically modified microorganisms which produce the compounds of the invention and means for the preparation of those microorganisms.
Mcalpine J. B.
Weber J. M.
Abbott Laboratories
Goudreau Gage Dubuc
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