C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/505 (2006.01) A61K 47/18 (2006.01)
Patent
CA 2558985
The invention relates to erythropoietin liquid formulations that are stable in storage and to a method for the production thereof. The invention particularly relates to erythropoietin liquid formulations, which contain at least four amino acids selected from the group consisting of leucine, isoleucine, threonine, glutamic acid, aspartic acid and phenylalanine, and in which the addition of preservatives, urea or human serum albumine can be foregone.
L'invention concerne des formulations liquides d'érythropoïétine, stables au stockage, ainsi que des procédés pour leur production. L'invention concerne en particulier des formulations liquides d'érythropoïétine qui contiennent au moins quatre acides aminés sélectionnés dans le groupe comprenant la leucine, l'isoleucine, la thréonine, l'acide glutamique, l'acide aspartique et la phénylalanine, et dans lesquelles il est possible de renoncer à l'adjonction de conservateurs, d'urée ou de sérumalbumine humaine.
Hesse Jan-Ole
Schumann Christof
Bioceuticals Arzneimittel Ag
Ridout & Maybee Llp
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