C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01)
Patent
CA 2501984
The present invention relates to antibodies and antibody fragments thereof that bind to and activate an erythropoietin receptor. The present invention also relates to methods of modulating the endogenous activity of an erythropoietin receptor in a mammal using said antibodies as well as pharmaceutical compositions containing said antibodies.
La présente invention concerne des anticorps et leurs fragments, qui se lient à et activent un récepteur de l'erythropoïétine. Elle concerne également des procédés mettant en oeuvre ces anticorps pour moduler l'activité endogène d'un récepteur de l'erythropoïétine chez un mammifère; et des compositions pharmaceutiques contenant lesdits anticorps.
Devries Peter J.
Green Larry L.
Ostrow David H.
Reilly Edward B.
Wieler James
Abbott Laboratories
Torys Llp
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