Esmolol formulation

Details Esmolol formulation Esmolol formulation

A - Human Necessities

61

K

A61K 31/216 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2410446

An aqueous, sterile pharmaceutical composition suitable for parenteral administration for the treatment of cardiac conditions, comprising methyl-3-[4- (2-hydroxy-3-isopropylamino) propoxy] phenylpropionate hydrochloride (esmolol hydrochloride), a buffering agent and an osmotic-adjusting agent, as well as a method for its manufacture, are disclosed.

L'invention porte sur une composition pharmaceutique, stérile, aqueuse, appropriée pour être administrée par voie parentérale dans le traitement de maladies cardiaques. Cette composition comprend un hydrochlorure méthyl-3-[4-(2-hydroxy-3-isopropylamino) propoxy] phénylpropionate (hydrochlorure d'esmolol), un tampon et un agent de régulation osmotique. Cette invention porte égalemtn sur un procédé de fabrication de cette composition.

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