Esr1 and cervical cancer

Details Esr1 and cervical cancer Esr1 and cervical cancer

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2574165

The present invention provides methods and kits for detecting susceptibility to, or the incidence of, cervical cancer in a sample comprising determining the methylation status of the ESR1 gene, optionally as part of a panel of genes. Also provided are methods and kits which involve determining the expression levels of genes including the ESR1 gene in order to diagnose cervical cancer.

L'invention concerne des procédés et des kits permettant de détecter une prédisposition au cancer cervical ou l'incidence de celui-ci dans un échantillon et consistant à déterminer l'état de méthylation du gène ESR1, éventuellement comme partie d'un ensemble de gènes. L'invention concerne également des procédés et des kits consistant à déterminer les niveaux d'expression de gènes, notamment le gène ESR1, afin de diagnostiquer un cancer cervical.

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