Essential oligonucleotides of vertebrate telomerase

Details Essential oligonucleotides of vertebrate telomerase Essential oligonucleotides of vertebrate telomerase

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 31/70 (2006.01) A61K 38/45 (2006.01) A61K 48/00 (2006.01) C12N 9/12 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2221602

DNA sequences encoding truncated RNA oligonucleotides of the vertebrate telomerase RNA component essential for the function of vertebrate telomerase are disclosed and their uses described. Vertebrate telomerase produced by combining an RNA oligonucleotide or an isolated RNA component with vertebrate telomerase protein is also disclosed.

L'invention porte sur des séquences d'ADN codant pour des oligonucléotides d'un ARN tronqué correspondant à la partie ARN de la télomérase de vertébré qui est essentielle pour son fonctionnement, ainsi que l'utilisation de ces oligonucléotides. L'invention porte également sur la télomérase de vertébrés produite en combinant l'oligonucléotide d'ARN ou la partie ARN isolée avec la protéine de cette télomérase de vertébré.

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